Jove
Visualize
Contact Us

Related Experiment Videos

Doxycycline prophylaxis in fracture surgery.

J Belsheim, H Gnarpe, O Hägg

    Scandinavian Journal of Infectious Diseases
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Characteristics and predicted outcome of patients lost to follow-up after degenerative lumbar spine surgery.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2020
    Same author

    ISSLS prize in clinical science 2020: the reliability and interpretability of score change in lumbar spine research.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2019
    Same author

    Follow-up of degenerative lumbar spine surgery-PROMs stabilize after 1 year: an equivalence study based on Swespine data.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2019
    Same author

    The value of patient global assessment in lumbar spine surgery: an evaluation based on more than 90,000 patients.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2017
    Same author

    Pain-drawing does not predict the outcome of fusion surgery for chronic low-back pain: a report from the Swedish Lumbar Spine Study.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2003
    Same author

    The clinical importance of changes in outcome scores after treatment for chronic low back pain.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2003
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Prophylactic doxycycline did not reduce postoperative infections in patients with fractured femurs. This study found no significant benefit of using doxycycline before surgery for hip fracture repair.

    Area of Science:

    • Orthopedic Surgery
    • Infectious Disease Prevention
    • Pharmacology

    Background:

    • Postoperative infections are a significant complication following orthopedic surgery, particularly hip fracture repair.
    • Preventive antibiotic strategies are crucial in reducing surgical site infections.

    Purpose of the Study:

    • To evaluate the efficacy of doxycycline as a prophylactic agent against postoperative infections in patients undergoing surgery for fractured collum femoris (femoral neck fracture).

    Main Methods:

    • A prospective study involving 64 patients receiving preoperative doxycycline as a preventive measure.
    • A control group of 46 patients did not receive doxycycline.
    • Comparison of the overall incidence of postoperative infection between the treated and control groups.

    Related Experiment Videos

    Main Results:

    • The incidence of postoperative infection was 6.3% in the group treated with doxycycline.
    • The incidence of postoperative infection was 6.5% in the control group.
    • No statistically significant difference in infection rates was observed between the two groups.

    Conclusions:

    • Preventive preoperative administration of doxycycline does not offer a significant advantage in reducing postoperative infections for patients with fractured collum femoris.
    • Current prophylactic antibiotic protocols for femoral neck fracture surgery may not require the addition of doxycycline.