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Ventricular premature beats and mortality of men with coronary heart disease

W Ruberman, E Weinblatt, C W Frank

    Circulation
    |December 1, 1975
    PubMed

    Insights

    Longer electrocardiogram (ECG) monitoring detects more ventricular premature beats (VPB) in men with coronary heart disease, identifying a higher-risk group. This improved detection correlates with increased mortality, even when routine ECGs miss the ectopic activity.

    Area of Science:

    • Cardiology
    • Preventive Medicine
    • Clinical Electrophysiology

    Background:

    • Coronary heart disease (CHD) poses significant mortality risks.
    • Ventricular premature beats (VPB) are potential indicators of cardiac risk.
    • Routine electrocardiogram (ECG) may underestimate the prevalence of VPB.

    Purpose of the Study:

    • To determine the frequency and characteristics of VPB in men with CHD.
    • To assess the relationship between VPB detection and mortality.
    • To compare the diagnostic yield of prolonged ECG monitoring versus routine ECG.

    Main Methods:

    • Analysis of 1-hour ECG monitoring in 924 men with CHD.
    • Correlation of VPB presence and frequency with mortality data.
    • Comparison of findings with results from standard 12-lead ECGs.

    Main Results:

    • Prolonged ECG monitoring identified ectopic activity in 52% of men, compared to 15% with routine ECG.
    • Men with VPB during monitoring exhibited higher mortality than those without.
    • Mortality risk was elevated in men with ≥10 VPB/hour, irrespective of routine ECG findings.

    Conclusions:

    • Extended ECG monitoring is superior to routine ECG for detecting VPB in CHD patients.
    • VPB identified through longer monitoring are associated with increased mortality.
    • Routine ECG may miss significant VPB, underestimating cardiac risk in CHD populations.

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