[Experiences with Pirenzepin in the therapy of peptic ulcers (author's transl)]

21 patients with peptic ulcers were treated with 2X25 mg Pirenzepin daily. A decrease in basal and Pentagastrin-stimulated HCl-secretion was found. Patients with duodenal ulcers (n = 12) or gastric ulcers (n = 9) became painless within 6 to 11 days. 18 ulcers healed under treatment with Pirenzepin. Patients with duodenal ulcer showed recovery sooner than patients with gastric ulcer. One year later recurrent ulcers were observed in 4 cases. Side-effects of Pirenzepin did not occur.