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Related Concept Videos

Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
The Stanford Prison Experiment03:20

The Stanford Prison Experiment

The famous and controversial Stanford Prison Experiment, conducted by social psychologist Philip Zimbardo and his colleagues at Stanford University, demonstrated the power of social roles, social norms, and scripts.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Unusual Results01:16

Unusual Results

Unusual results are those that have a very low chance of occurring. Unusual results can be identified using probabilities and the range rule of thumb. In problems involving probability, unusual results can be observed in 2 instances – an unusually high number of successes or an unusually low number of successes.
According to the range rule of thumb, any value above or below two standard deviations, 2σ  from the mean, μ  is considered unusual.
Maximum unusual value = μ + 2σ
Minimum unusual value...
Ending Relationships01:28

Ending Relationships

The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...

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Related Experiment Video

Updated: Jun 25, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
05:42

The Forced Swim Test as a Model of Depressive-like Behavior

Published on: March 2, 2015

[An unusual suicidal attempt (author's transl)].

R Langer

    Wiener Medizinische Wochenschrift (1946)
    |October 30, 1979
    PubMed
    Summary

    This case report details a rare suicidal attempt using a grinding disc, resulting in severe neck and wrist injuries. Prompt medical intervention was crucial for the patient

    Area of Science:

    • Forensic Pathology
    • Trauma Surgery

    Context:

    • Presents a unique case of self-inflicted injury using a high-power tool.
    • Highlights the severe consequences of using a separating disc for self-harm.

    Purpose:

    • To document an unusual method of suicidal attempt.
    • To emphasize the critical role of immediate medical response in survivability.

    Summary:

    • A patient survived a severe suicidal attempt involving a separating (grinding) disc.
    • Injuries included bilateral wrist lacerations, occipital wounds, and a transected hypopharynx and left jugular vein.
    • Successful resuscitation was attributed to rapid physician intervention.

    Impact:

    • Illustrates the potential for severe harm from common tools used in self-harm.

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  • Underscores the importance of prompt emergency care for complex trauma cases.