Effects of essential fatty acid deficiency on various functions of the rat erythrocyte membrane
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Updated: Aug 12, 2026

Dietary Supplementation of Polyunsaturated Fatty Acids in Caenorhabditis elegans
Published on: November 29, 2013
Abstract:
Various membrane transport functions have been studied in erythrocytes from essential fatty acid (EFA) deficient rats in order to determine whether or not functional abnormalities induced by documented EFA-deficiency of the membrane could be demonstrated. No differences were found between EFA deficient and control cells with respect to mean values for osmotic resistance or intracellular sodium and potassium concentrations. However, uptake of leucine by EFA deficient erythrocytes was significantly greater than that of control erythrocytes. Kinetic studies suggest that EFA deficiency enhances the passive diffusion component of this transport.
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