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Esophageal dysfunction in diabetes mellitus.

S Forgács, Z Kéri, J Osváth

    Acta Diabetologica Latina
    |July 1, 1979
    PubMed
    Summary

    Diabetes can cause esophageal dysfunction, including prolonged transit times and abnormal contractions, often linked to diabetic visceral neuropathy affecting the vagus nerve. These changes appear earlier and more frequently in diabetic patients.

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    Area of Science:

    • Gastroenterology
    • Endocrinology
    • Neurology

    Background:

    • Diabetes mellitus is a systemic disease with diverse complications.
    • Diabetic visceral neuropathy can affect gastrointestinal motility.
    • Esophageal dysfunction is a potential, oftensubtle, manifestation of diabetes.

    Purpose of the Study:

    • To investigate esophageal motility and structure in diabetic patients.
    • To compare findings in diabetic patients with a control group.
    • To explore the relationship between esophageal abnormalities and diabetic neuropathy.

    Main Methods:

    • Detailed roentgenological examinations of the esophagus were performed.
    • 110 diabetic patients and 130 control subjects were included.
    • Esophageal transit time and functional abnormalities were assessed.

    Main Results:

    • 45% of diabetic patients showed functional esophageal abnormalities.
    • Abnormalities included wavy contours, irregular contractions, and functional diverticula.
    • Esophageal transit time was significantly prolonged in diabetics, occurring at an earlier age and more frequently than in controls.

    Conclusions:

    • Diabetic dysphagia is a manifestation of diabetic visceral neuropathy.
    • Damage to the vagus nerve is the primary cause of these esophageal changes.
    • Esophageal dysfunction in diabetes warrants clinical consideration despite mild or absent symptoms.

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