Related Experiment Video
Updated: Aug 13, 2026

Cantilever Bending of Murine Femoral Necks
Published on: January 5, 2022
Bone-marrow pressure and bone strength
Abstract:
The pattern of bone-marrow pressure changes differed with the mode of stress application. Intra-medullary pressure remained steady during most of the slow loading. During rapid dynamic loading, however, a slight rise in intra-medullary pressure was observed. Contraction of the femoral muscles also resulted in a greater bone-marrow pressure increase. A correlation of 0.98 (P less than 0.001) between stimulus strength and intra-medullary pressure was obtained. The rise in intra-medullary pressure with femoral muscle contraction is suggested to have a possible role under extreme stresses in living conditions.
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