Evaluation of the anti-emetic action of domperidone

The findings of a study into the anti-emetic properties of domperidone are reported. When the drug was given prophylactically with either morphine or pethidine the study revealed that any anti-emetic property of domperidone was of short duration and that it would not be suitable as a prophylaxis against opiate-induced emesis. Domperidone is not being introduced into clinical practice in the United Kingdom on the basis of current study.