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Volume replacement in acute anaphylactoid reactions.

M M Fisher, I Dicks

Anaesthesia and Intensive Care

|November 1, 1979

Summary

Cardiovascular collapse from anaphylactoid reactions requires both sympathomimetics and colloid solutions for circulatory restoration. These treatments effectively managed haemoconcentration in two critical patients.

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Area of Science:

Anesthesiology
Emergency Medicine
Critical Care

Background:

Anaphylactoid reactions can lead to severe cardiovascular collapse.
Haemoconcentration is a key indicator of circulatory compromise in these reactions.

Observation:

Two patients presented with cardiovascular collapse and haemoconcentration due to anaphylactoid reactions.
The first patient's haemoconcentration resolved with colloid solutions and vasoconstrictors.
The second patient required colloid solutions for circulatory restoration despite crystalloid and adrenaline administration.

Findings:

Circulatory restoration in acute anaphylactoid reactions necessitates the combined use of sympathomimetics and colloid solutions.
Colloid solutions were crucial for managing haemoconcentration when crystalloids were insufficient.

Implications:

This highlights the critical role of colloid solutions in managing anaphylactoid-induced cardiovascular collapse.
Optimal treatment strategies should incorporate both sympathomimetics and aggressive fluid resuscitation with colloids.

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