[Reaction of the elements of the hypophyseal-adrenal system in "starting" states]

Morphological elements of the system hypophysis--adrenals have been studied in 19 dogs. Nine animals were given single individually dosed physical loading (running in the treadmill) up to the III stage according to an original technique. The III stage of the organism's response is characterized, according to physiological and biochemical parameters, as a "starting" condition. The other 10 animals served as a control. Biometric, histologic, histoenzymatic and electron microscopic methods were used for the study. The "starting" conditions were demonstrated to determine variously directed dynamics and unequal involvment of cellular elements and zones of the system hypophysis--adrenals. The greatest reactive degree was noted in basophilic adenocytes and chromophobes, as well as in the medullar substance of the adrenals. Acidophils and cells of the fascicular zone play the least role in the response. Unequal participation of the adenohypophyseal cellular elements and the adrenal zones in the organism's response at the "starting" conditions form a predominance of certain processes of cellular activity in them.