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Ocular involvement in scleroderma.

R H West, A J Barnett

    The British Journal of Ophthalmology
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Ophthalmic assessments revealed frequent abnormalities in scleroderma patients. Scleroderma-related eye changes include eyelid, tear secretion, and conjunctival issues, impacting vision.

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    Area of Science:

    • Ophthalmology
    • Rheumatology
    • Systemic Sclerosis Research

    Background:

    • Scleroderma, or progressive systemic sclerosis, is an autoimmune disease affecting connective tissues.
    • Ocular manifestations in scleroderma can significantly impact patient quality of life.
    • Previous research indicates a range of eye abnormalities in scleroderma patients, but comprehensive assessments are needed.

    Purpose of the Study:

    • To conduct a detailed clinical ophthalmic assessment of patients with scleroderma.
    • To identify and categorize ocular abnormalities specifically related to scleroderma.
    • To investigate the correlation between skin involvement extent and observed eye changes.

    Main Methods:

    • Detailed clinical ophthalmic examinations were performed on 38 patients with scleroderma.

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  • Patients were assessed for various ocular parameters, including eyelid, tear secretion, conjunctival, and iris abnormalities.
  • Ocular findings were analyzed in relation to scleroderma diagnosis and disease severity (skin involvement).

    • Main Results:

    • Frequent ophthalmic abnormalities were observed in scleroderma patients.
    • Scleroderma-related changes included eyelid abnormalities (stiffness, telangiectasia), deficient tear secretion, and conjunctival abnormalities (injection, vascular sludging).
    • Iris light reflux was also possibly linked to scleroderma, with changes correlating to the extent of skin involvement.

    Conclusions:

    • Scleroderma frequently causes specific ocular abnormalities affecting the eyelids, tear film, and conjunctiva.
    • These findings underscore the importance of regular ophthalmic screening for scleroderma patients.
    • Understanding these eye changes can aid in managing the systemic effects of scleroderma.