Plasmapheresis combined with corticosteroids and cyclophosphamide in uncontrolled active systemic lupus erythematosus

A case is described of severe systemic lupus erythematosus, uncontrolled with moderate dosage of corticosteroid and cyclophosphamide, which responded quickly after 3 courses of plasmapheresis. The result obtained with combination corticosteroids, cyclophosphamide and plasmapheresis was maintained for more than 18 months.