Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hydronephrosis in ACI/N rats.

K Fujita, H M Fujita, Y Ohtawara

    Laboratory Animals
    |October 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Plasma cfDNA analysis of alectinib resistance-related gene alterations in the J-ALEX study.

    ESMO open·2025
    Same author

    Developmental potential of cryopreserved gonadal germ cells from 7-day-old chick embryos recovered using the PBS(-) method.

    British poultry science·2021
    Same author

    A toddler with phylloid-type pigmentary mosaicism and ambiguous genitalia resulting from trisomy 14 induced by a der(Y)t(Y;14).

    Human genome variation·2020
    Same author

    A Targeted Genetic Association Study of the Rare Type of Osteomyelitis.

    Journal of dental research·2020
    Same author

    Effect of media composition, including gelling agents, on isolation of previously uncultured rumen bacteria.

    Letters in applied microbiology·2012
    Same author

    Physical and biological studies on DNA/anti-DNA immune complex formed in vitro.

    Cytotechnology·2012
    Same journal

    Standardized surgical access to the porcine temporomandibular joint: Anatomical basis for translational research.

    Laboratory animals·2026
    Same journal

    Development of animal use in experiments: a brief historical overview.

    Laboratory animals·2026
    Same journal

    The reduction potential of diet board feeding-survival and clinical chemistry of group-housed Sprague Dawley rats in a 24-month study.

    Laboratory animals·2026
    Same journal

    Advancing the 3Rs? Researchers' perspectives on institutional facilitation in Switzerland - Part 2: executive facilitation.

    Laboratory animals·2026
    Same journal

    Recognition of pain and distress.

    Laboratory animals·2026
    Same journal

    Strengthening animal welfare: monitoring humane endpoints in a rat model of mammary tumorigenesis undergoing a ladder resistance training protocol.

    Laboratory animals·2026
    See all related articles

    Renal agenesis and hydronephrosis were observed in 9 and 2 out of 45 rats, respectively. Faulty mesonephric duct development may cause hydronephrosis in rats.

    Area of Science:

    • Developmental biology
    • Comparative pathology
    • Toxicology

    Background:

    • Renal agenesis is a congenital condition where one or both kidneys fail to develop.
    • Hydronephrosis is a condition characterized by swelling of a kidney due to a backup of urine.
    • The mesonephric duct plays a crucial role in early kidney development.

    Purpose of the Study:

    • To investigate the incidence of renal agenesis and hydronephrosis in a specific rat strain.
    • To explore potential causes of observed renal abnormalities, including faulty mesonephric duct development.

    Main Methods:

    • A cohort of 45 ACI/N rats was examined.
    • Macroscopic examination was performed to identify renal abnormalities.

    Main Results:

    Related Experiment Videos

    • Renal agenesis was detected in 9 out of 45 rats (20%).
    • Hydronephrosis was observed in 2 out of 45 rats (4.4%).

    Conclusions:

    • ACI/N rats exhibit a notable incidence of renal agenesis.
    • Faulty development of the mesonephric duct is a potential contributing factor to hydronephrosis in this rat model.