Ultrastructure of acetylcholinesterase containing striato-nigral neurons transporting HRP retrogradely

The fine structure of striato-nigral efferent neurons, retrogradely labeled with HRP, was studied. The neuron showed a medium sized ovoid or tri-angular perikaryon. Short or medium lengthened granular endoplasmic reticula, having a tendency to wind and pile up in stacks were observed. This neurons corresponds to a type III neuron according to our classification [4,5]. The neuron showed reaction products, indicating AChE activity, in the granular endoplasmic reticula and plasma membrane.