Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Timolol--further observations.

T J Zimmerman, P Canale

    Ophthalmology
    |January 1, 1979
    PubMed
    Summary

    Timolol effectively lowers eye pressure in various glaucoma types and ocular hypertension. This study found no significant side effects, and tachyphylaxis was rare with timolol therapy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Editorial expression of concern: Monocytes and lymphocytes as active participants in the pathogenesis of experimental shock.

    Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2024
    Same author

    Family Pediatrician and Public Health collaboration, an alliance to increase vaccination coverage: an experience with MenB vaccination in Italy.

    Annali di igiene : medicina preventiva e di comunita·2021
    Same author

    Interaction between nickel and iron in the rat.

    Biological trace element research·2013
    Same author

    Interactions among nickel, copper, and iron in rats : Growth, blood parameters, and organ wt/body wt ratios.

    Biological trace element research·2013
    Same author

    Interactions among nickel, copper, and iron in rats : Liver and plasma content of lipids and trace elements.

    Biological trace element research·2013
    Same author

    The glaucoma medications of the next century.

    Journal of glaucoma·2009

    Area of Science:

    • Ophthalmology
    • Pharmacology

    Background:

    • Glaucoma is a leading cause of irreversible blindness.
    • Effective management of intraocular pressure (IOP) is crucial for preventing glaucomatous optic nerve damage.
    • Timolol is a beta-adrenergic blocker commonly used in glaucoma treatment.

    Purpose of the Study:

    • To evaluate the efficacy of timolol in reducing ocular hypotensive pressure.
    • To assess the safety profile of timolol in patients with various forms of glaucoma.
    • To determine the frequency of tachyphylaxis with long-term timolol use.

    Main Methods:

    • Retrospective analysis of clinical records.
    • Inclusion of patients with secondary glaucoma, aphakic glaucoma, ocular hypertension, and those on combination therapy.
    • Monitoring for local and systemic side effects.

    Main Results:

    • Timolol demonstrated significant ocular hypotensive effects across diverse glaucoma subtypes.
    • The drug was well-tolerated, with no serious local or systemic adverse events reported.
    • Tachyphylaxis, a decrease in drug response over time, was infrequently observed.

    Conclusions:

    • Timolol is a safe and effective agent for lowering intraocular pressure in multiple glaucoma conditions.
    • Its favorable side effect profile and low incidence of tachyphylaxis support its continued use in glaucoma management.

    Related Experiment Videos