[Behavior of glycoproteins and blood serum proteins in rats after PVC implantation]

Determination of soluble protein level and bound sialic acid in 0,15 M SSA (seromucoid) as well as of protein levels and total sialic acid (NANA) were made both in blood serum and serous fluid. These tests were performed before and after subcutaneous and intra-abdominal implantation of different PVC samples. The subcutaneous implantation of samples caused the appearance of serous fluid and subsequently inflammation characterized by an increase of levels of sialic acid and seromucoid--the so-called "acute protein reaction". There were also observed the increased electrophoretic alpha 1, alpha 2 and beta globulin levels. Intra-abdominal implantation caused a decrease in the sialic acid level. Also the albumin fraction decreased but the concentration of the alpha 1 globulin fraction stayed within normal limits.