[Histopathological picture of acute disseminated intravascular coagulation]

The paper deals with histological analysis of 72 cases characterized by the finding of capillary microthromboses characteristic of acute disseminated intravascular coagulation (DIC). It has been stressed that, in addition to the usual fibrillary fibrin deposits, DIC is also characterized by the occurrence of globular fibrin formations, most frequently found within the hepatic and hypophyseal sinusoids. In the present series, microthromboses were obviously more frequent within the capillaries of organs such as the renal glomeruli or plexus chorioideus, wherein significant amounts of water are lost from circulating blood.