Effect of O-(beta-hydroxyethyl)-rutoside on wound healing in the rat

The administration of O-(beta-hydroxyethyl)-rutoside in 11 daily doses of 300--400 mg/kg p.o. stimulates wound healing by granulation in the rat. The preparation may counteract the inhibitory effect of prednisone on the formation of granulation tissue. In five doses of 300--1,000 mg/kg daily p.o. it augments the tensile strength of cicatricial tissue to a statistically significant degree.