Urological septicemia. A retrospective study

Area of Science:

• Urology
• Infectious Diseases
• Critical Care Medicine

Background:

• Urosepsis, a severe bloodstream infection originating from the urinary tract, poses a significant clinical challenge.
• Understanding the epidemiology and clinical outcomes of urosepsis in specific patient populations is crucial for effective management.

Purpose of the Study:

• To investigate the clinical course and outcomes of septicemia in patients within a specialized urological department.
• To identify risk factors, causative pathogens, and mortality rates associated with urosepsis.

Main Methods:

• Retrospective data collection from patients admitted to a urological department over a 5-year period.
• Inclusion criteria: patients with positive blood cultures indicating septicemia.
• Analysis of patient demographics, clinical presentation, causative agents, and treatment outcomes.

Main Results:

• Ninety-one cases of urosepsis were identified over 5 years, with an incidence of 1.2%.
• Gram-negative bacteria were the predominant pathogens (75%), especially in cases of septic shock (99%).
• Septic shock occurred in 20 patients, with an overall mortality of 3%, primarily in those with serious comorbidities.

Conclusions:

• Urosepsis in urological patients generally follows a benign clinical course with a low complication rate.
• Compared to gastroenterological patients, urosepsis appears to be a less severe condition in urological settings.
• The discrete diagnostic and therapeutic procedures in urology may contribute to the less severe outcomes observed.