Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Massive heroin intoxication. Hemodynamic studies].

G Bertona, G Domenighetti, P Reigner

Schweizerische Medizinische Wochenschrift

|December 8, 1979

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mapping of Dietary Interventions Beneficial in the Prevention of Secondary Health Conditions in Spinal Cord Injured Population: A Systematic Review.

The journal of nutrition, health & aging·2023

Same author

Fully endoscopic clipping of anterior circulation cerebral aneurysms through transpalpebral approach: One step closer to robotic neurovascular surgery?

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2021

Same author

Management of vascular and nonvascular complications following pancreas transplantation with interventional radiology.

Diagnostic and interventional imaging·2020

Same author

Minilaparotomy-assisted transmesenteric approach for portal vein recanalization and transjugular intrahepatic portosystemic shunt in a non-cirrhotic patient with portal cavernoma.

Diagnostic and interventional imaging·2020

Same author

Ultrasonographic guidance for portal vein access during transjugular intrahepatic portosystemic shunt (TIPS) placement.

Diagnostic and interventional imaging·2019

Same author

Erratum to "Storage at room temperature does not change cisatracurium onset time: A prospective, randomized, double-blind controlled study [Ann. Fr. Anesth. Reanim. 31 (2012) 783-787].

Anaesthesia, critical care & pain medicine·2018

Same journal

Respiratory function test in the case of temporary phrenic nerve contusion, associated with pneumoperitoneum; About the diagnostic value of laparoscopy.

Schweizerische medizinische Wochenschrift·2010

Same journal

Treatment of pulmonary tuberculosis and pleurisy by means of temporary paralysis of the diaphragm, supported by the pneumoperitoneum.

Schweizerische medizinische Wochenschrift·2010

Same journal

Boeck's disease as a tuberculous syndrome.

Schweizerische medizinische Wochenschrift·2010

Same journal

Enteral primary tubercular complexes

Schweizerische medizinische Wochenschrift·2010

Same journal

Tuberculous stenoses of the large bronchi.

Schweizerische medizinische Wochenschrift·2010

Same journal

About the enzyme action.

Schweizerische medizinische Wochenschrift·2010

See all related articles

Heroin overdose can cause severe acidosis and distinct hemodynamic changes. One patient experienced biventricular heart failure, while another showed pulmonary edema with a hyperdynamic state.

Area of Science:

Cardiology
Toxicology
Critical Care Medicine

Background:

Acute hemodynamic changes during heroin overdose are rarely documented.
Understanding these changes is crucial for effective patient management.

Observation:

Two young male patients presented with coma, shock, and severe mixed acidosis following heroin overdose.
Patient 1: pH 6.80, PaCO2 72 mmHg, PaO2 70 mmHg, BE -18 mEq/l, lactic acid 16.5 mmol/l.
Patient 2: pH 6.86, PaCO2 94 mmHg, PaO2 46 mmHg, BE -16 mEq/l, lactic acid 5.45 mmol/l.

Findings:

Patient 1 exhibited a low output cardiac failure with high filling pressures, indicative of biventricular heart failure.
Patient 2 presented with pulmonary edema, a hyperdynamic state, and elevated pulmonary artery pressure, but normal pulmonary capillary pressure.

Related Experiment Videos

Implications:

These distinct hemodynamic patterns suggest varied pathophysiological responses to heroin overdose.
Further research is needed to elucidate the mechanisms behind these differing cardiovascular presentations.