[Stable shifts in systemic arterial pressure in a controlled experiment with feedback]

On the bases of experiments with bio-control feed-back connection (automatically triggering electro-cutaneous, stimulation), a model evolved permitting to achieve stable directed changes in the levels of the systemic arterial pressure (AP) in curarized rabbits and cats. Two variants of reactions are possible: 1) gradual formation of a new raised or lowered level of AP with its pronounced retention after the end of learning, and 2) reaction of following type with directed rise in AP, which is observed only during learning. It is found that the stable shifts of the AP level are accompanied by changes in the periodicity of the third order AP waves, the heart rate showing no significant changes. It is assumed that the changes in the characteristics of the third order waves reflect the rearrangement of the mechanisms providing for homeostasis.