[Effect of anticholinergics on bladder tonus and on the voiding function]

When the anticholinergic drugs with an effect which above all peripherally and selectively affects the urinary bladder the following may be proved: 1. Increase of the capacity of the urinary bladder according to the initial situation, 2. no influence on the intravesical pressure in maximum filling of the bladder, 3. decrease of the maximum intravesical pressure during the miction, 4. decrease of the rate of the flow of the urine and 5. increase of the maximum urethral pressure as well as no influence on the functional length of the urethra. From these parameters the adequate clinical application in diseases of the urinary bladder may be derived and at a strong indication good successes in treatment can be achieved.