[Pregestational secretory change in endometrium in infertility (author's transl)]

The degree of secretory transformation in connection with infertility was studied by morphologico-histochemical analysis. The results seem to provide evidence to the effect that severe secretory insufficiency of surface epithelium is the major pathological phenomenon recordable from the endometrium in cases of infertility. Defective function of epithelial oestrogen receptors and disorders in endometrial regeneration during one cycle have to be taken into consideration regarding the pathogenesis of segmental insufficiency of secretory endometrial transformation. More elucidation will depend, last but not least, on immunological response which often lies within all endometrial strata.