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Published on: May 15, 2011
Myocardial infarction complicated by heart block--treatment and long-term prognosis
Insights
Heart block following acute myocardial infarction (AMI) worsens prognosis but survival is independent of block degree. Conservative treatment for complete heart block showed similar survival to aggressive pacing, questioning routine artificial pacing in AMI patients.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Acute myocardial infarction (AMI) can lead to various heart blocks.
- Continuous electrocardiogram (ECG) monitoring is standard in coronary care units.
Purpose of the Study:
- To investigate the incidence and prognostic impact of heart block in AMI patients.
- To evaluate the effectiveness of conservative versus aggressive pacing strategies for complete heart block in AMI.
Main Methods:
- Prospective monitoring of 597 AMI patients in a coronary care unit.
- Classification of heart block degrees (first, second, complete).
- Two-year survival tracing and comparison with a historical pacing group.
Main Results:
- 84 patients (14%) developed heart block; 39 had complete heart block.
- Heart block was associated with a worse two-year prognosis.
- Survival rates for complete heart block were similar between conservative treatment (including isoproterenol and temporary pacing) and a historical group receiving routine artificial pacing.
Conclusions:
- Heart block degree does not significantly impact two-year survival post-AMI.
- Indiscriminate artificial pacing for complete heart block in AMI is not supported by these findings.
- Further randomized controlled trials are warranted to confirm these results.
Abstract:
A number of 597 patients with acute myocardial infarction (AMI) were treated with continuous ECG monitoring of the heart rhythm in a coronary care unit for at least three days. We found 84 patients with heart block, 39 with complete, 29 with at most second degree and 16 with at most first degree heart block. The treatment was primarily conservative; 22 of the 39 patients with complete heart block were given isoproterenol and two received temporary pacemakers. Survival was traced over two years in the whole patient group with myocardial infarctions. Heart block implied a worsened prognosis over the two years, but survival was independent of the degree of heart block. Among those with complete heart block, survival did not differ from that of a comparable patient series from Copenhagen, where all patients were given pacemakers. This does not support indiscriminate artificial pacing of patients with AMI and complete heart block. Our results ought to be controlled in a randomized study.
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