Related Experiment Videos
[Severe allergic cutaneovisceral vasculitis in children. Apropos of 6 cases]
Archives Francaises De Pediatrie
|July 1, 1979
Insights
Allergic vasculitis in children presents with skin lesions and organ involvement. Severe cases may benefit from immunosuppression with cyclophosphamide when corticosteroids fail.
Area of Science:
- Pediatric Rheumatology
- Dermatology
- Immunology
Abstract:
Six children aged between 10 months and 13 years with allergic vasculitis are described. The features they had in common were necrotic skin lesions, involvement of various viscera and signs of hypersensitivity reactions. Histological changes of allergic vasculitis were present in the small vessels of the skin. This condition has features in common with both polyarteritis nodosa and with anaphylactoid purpura. Severe cases that do not respond to corticosteroids may respond to immuno-suppression with cyclophosphamide.