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Initial experiences with continuous ambulatory peritoneal dialysis.

S S Fenton, D C Cattran, A F Allen

    Artificial Organs
    |August 1, 1979
    PubMed
    Summary
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    Continuous ambulatory peritoneal dialysis (CAPD) is effective for end-stage renal disease patients, improving creatinine and BUN levels. However, peritonitis and fluid balance issues can limit its use.

    Area of Science:

    • Nephrology
    • Internal Medicine

    Background:

    • Continuous ambulatory peritoneal dialysis (CAPD) is an alternative treatment for end-stage renal disease (ESRD).
    • Patient outcomes and complications associated with CAPD require ongoing evaluation.

    Purpose of the Study:

    • To assess the efficacy and complications of Continuous ambulatory peritoneal dialysis (CAPD) in a cohort of 51 patients with end-stage renal disease.
    • To evaluate the impact of CAPD on biochemical parameters and compare it with intermittent peritoneal dialysis.

    Main Methods:

    • Observational study of 51 ESRD patients undergoing CAPD for a total of 1420 patient-weeks.
    • Monitoring of peritonitis episodes, fluid balance control, and changes in serum creatinine, BUN, and hemoglobin levels.

    Main Results:

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    • Thirty-six peritonitis episodes occurred in 19 patients (incidence: 1 per 39.4 patient-weeks).
    • CAPD was discontinued in 9.8% due to recurrent peritonitis and 5.9% due to fluid imbalance.
    • Patients transferring from intermittent peritoneal dialysis to CAPD showed improved serum creatinine (-4.5 mg/dl), BUN (-34 mg/dl), and hemoglobin (+2 gm).

    Conclusions:

    • CAPD demonstrates positive effects on key biochemical markers in ESRD patients.
    • Peritonitis and extracellular fluid balance remain significant challenges for CAPD.
    • Addressing peritonitis could establish CAPD as a preferred dialysis modality for many ESRD patients.