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Updated: Aug 19, 2026

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Increased intraventricular pressure without ventriculomegaly in children with shunts: "normal volume" hydrocephalus
Insights
Patients with shunt-dependent hydrocephalus can have normal ventricular size despite high pressure due to shunt malfunction. This "normal volume" hydrocephalus indicates high elastance and requires urgent surgical intervention.
Area of Science:
- Neurosurgery
- Pediatric Neurology
- Biomedical Engineering
Background:
- Hydrocephalus is a condition characterized by excessive cerebrospinal fluid (CSF) accumulation in the brain's ventricles.
- Shunt systems are commonly used to treat hydrocephalus by draining excess CSF.
- Shunt malfunction can lead to dangerously elevated intracranial pressure.
Observation:
- Five patients with shunt-dependent hydrocephalus presented with normal ventricular size despite significant increases in ventricular pressure after shunt malfunction.
- Elastance, a measure of ventricular wall stiffness (dP/dV), was assessed in four patients by measuring pressure changes after CSF withdrawal.
Findings:
- Patients exhibiting normal ventricular volume with markedly increased ventricular pressure demonstrated high elastance.
- This specific presentation, termed "normal volume" hydrocephalus, was associated with distal shunt occlusions.
- Common factors included initial shunting in infancy, prolonged shunt dependency, and absence of recent shunt revisions.
Implications:
- Elevated intracranial pressure with normal ventricular volume represents a critical clinical scenario.
- Prompt surgical intervention is necessary for patients with "normal volume" hydrocephalus to prevent neurological damage.
- Understanding shunt mechanics and patient history is crucial for diagnosing and managing this condition.
Abstract:
Five patients with shunt-dependent hydrocephalus were observed to have apparently normal ventricular size despite marked increases in ventricular pressure after shunt malfunction. Elastance (dP/dV) was determined in four of these patients by removing increments of cerebrospinal fluid and measuring the resulting pressure. These patients without ventricular enlargement and with markedly increased ventricular pressure had high elastance. This group of patients with "normal volume" hydrocephalus had distal shunt occlusions, in contrast to previously reported patients with cephalic shunt obstructions after ventricular decompression. Initial shunting in early infancy, prolonged shunt dependency, and lack of recent shunt revision were common factors in these patients. Markedly elevated pressure with normal volume is a threatening clinical entity, requiring prompt surgical intervention
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