Needle biopsy under computerized tomographic control: a method for tissue diagnosis in intracranial lesions

Area of Science:

• Neurosurgery
• Neuroradiology
• Oncology

Background:

• Intracranial lesions require accurate diagnosis for effective treatment.
• Minimally invasive biopsy techniques aim to reduce procedural risks.
• Computerized tomography (CT) provides crucial visualization for intracranial procedures.

Purpose of the Study:

• To evaluate the efficacy and safety of CT-guided twist drill needle biopsy for diagnosing intracranial lesions.
• To determine the diagnostic yield and complication rate of this minimally invasive technique.

Main Methods:

• Thirteen patients with intracranial lesions underwent CT-guided twist drill needle biopsy under sedation and local anesthesia.
• Biopsies were performed using a twist drill needle under real-time CT control.
• Patients received dexamethasone pre- and post-procedure to manage potential edema.

Main Results:

• Definitive diagnoses were obtained in 11 out of 13 patients (85%).
• Diagnoses included glioblastoma (7 patients) and other various intracranial pathologies.
• The only significant complication was transient limb weakness in 4 patients; one patient had an asymptomatic intracranial hematoma.

Conclusions:

• CT-guided twist drill needle biopsy is a safe and effective method for diagnosing a wide range of intracranial lesions.
• The procedure facilitates timely therapeutic interventions, avoiding the need for further surgery in most cases.