Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular abnormalities occurring with vitiligo.

D M Albert, J J Nordlund, A B Lerner

    Ophthalmology
    |June 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The ultraviolet absorption of the plasma proteins.

    Archives of biochemistry·2010
    Same author

    A homomolecular serum protein with anomalous solubilities.

    The Journal of biological chemistry·2010
    Same author

    Studies of cryoglobulins; unusual purpura associated with the presence of a high concentration of cryoglobulin (cold precipitable serum globulin).

    The American journal of the medical sciences·2010
    Same author

    Studies of cryoglobulins the spontaneous precipitation of protein from serum at 5 degrees C in various disease states.

    The American journal of the medical sciences·2010
    Same author

    A new rapid method for the determination of serum albumin and globulin by ultraviolet absorption.

    Archives of biochemistry·2010
    Same author

    With a perfect start. Dermatology at Yale 1955-1985.

    Journal of the American Academy of Dermatology·2001
    Same journal

    Metastasis of Nasopharyngeal Squamous Cell Carcinoma to the Angle.

    Ophthalmology·2026
    Same journal

    Endocrine Mucin-Producing Sweat Gland Carcinoma of Eyelid.

    Ophthalmology·2026
    Same journal

    Multimodal Imaging of Optic Nerve Invasion in Unilateral Retinoblastoma.

    Ophthalmology·2026
    Same journal

    Avacincaptad Pegol Slows Progressive Ellipsoid Zone Degradation/Loss in Eyes With Geographic Atrophy.

    Ophthalmology·2026
    Same journal

    Access to Intravitreal Anti-VEGF Drugs in Persons with Medicare Advantage Compared with Medicare Fee-For-Service.

    Ophthalmology·2026
    Same journal

    Re: Dones et al.: Emergency department use of ocular point-of-care ultrasound and its utility in diagnosis at a tertiary academic medical center (Ophthalmology. 2026;133:720-727).

    Ophthalmology·2026
    See all related articles

    Vitiligo patients often show ocular abnormalities, including depigmentation and uveitis. These findings suggest a broader spectrum of disease linking vitiligo with uveal inflammation, potentially including Harada

    Area of Science:

    • Ophthalmology
    • Dermatology
    • Autoimmune Diseases

    Background:

    • Vitiligo is a condition characterized by depigmentation of the skin.
    • Ocular manifestations in vitiligo patients are not fully understood.
    • Conditions like Harada's disease and Vogt-Koyanagi syndrome involve both ocular and dermatological symptoms.

    Purpose of the Study:

    • To investigate the prevalence and nature of ocular abnormalities in patients with vitiligo.
    • To explore the potential link between vitiligo and inflammatory ocular diseases.
    • To assess if vitiligo represents a broader spectrum of conditions involving uveal inflammation.

    Main Methods:

    • Examination of 112 patients diagnosed with vitiligo for ocular abnormalities.
    • Clinical assessment of depigmentation, pigment hyperplasia, and uveitis.

    Related Experiment Videos

  • Evaluation of symptoms such as night blindness and family history of retinitis pigmentosa.

    • Main Results:

    • Ocular abnormalities were observed in a significant portion of vitiligo patients.
    • Discrete areas of depigmentation and pigment hyperplasia involving the choroid and retinal pigment epithelium were noted in 44 patients.
    • Active uveitis was diagnosed in nine patients, with some reporting night blindness.

    Conclusions:

    • The findings suggest a wider spectrum of diseases encompassing vitiligo and uveal inflammatory conditions.
    • Vitiligo patients may represent severe cases of autoimmune conditions affecting both skin and eyes.
    • Evidence points towards potential retinal pigment epithelium dysfunction in some vitiligo patients, indicated by night blindness and prominent choroidal patterns.