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Elution of glomerular bound antibodies in experimental streptococcal glomerulonephritis

Science (New York, N.Y.)
|November 21, 1969
PubMed

lmmnunoglobulin G, eluted from glomeruli of rats with streptococcal glomerulonephritis, reacts with type 12 M protein of the streptococcus but not with other streptococcal or renal antigens. Thtrefore, this disease may be madiated by fixation of antigen-antibody complexes consisting of streptococcal M protein and type-specific antibody.

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