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Updated: Aug 18, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Vaginal metastases as the ist signs of primary occult hypernephroid kidney neoplasms]
Abstract:
Based on the literature and own observations it is pointed out that in cases of vaginal tumors as a rule a consequent search for tumors of the kidneys is necessary, because vaginal tumors may be metastases of primarily not identified hypernephroid carcinomas. The frequency of such metastases is reported to be about 2%. A search for kidney tumors is necessary, if histological findings of the vaginal tumor are clearly suspect for hypernephroid carcinoma, or if it cannot be clearly identified as a primary vaginal tumor or--as a metastasis--gives no certainty to be a metastasis of a primary tumor of other localization. Because of the relative statistical frequency of vaginal metastases from carcinomas of the kidneys a consiliary gynecological check up is necessary if the diagnosis of the tumor was primarily a urologic one to ensure that there are no vaginal metastases. Further diagnostic and therapeutic procedures are discussed.
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