Early diagnosis of multiple sclerosis by combined multimodal evoked potentials: results and practical considerations

It is shown that using four combined types of evoked potentials one can disclose new localisations in 62.5% of as yet undiagnosed M.S. patients. Brainstem auditory EP recordings must be considered in detail to avoid missing slight anomalies. Blink reflexes yielding bilateral R1 seem to bear the same significance as an augmented latency with respect to the problem of disclosing new localisations.