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[Bone changes in hemoblastoses and malignant lymphomas].

L Stenzel, K Krug, J Franke

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |July 15, 1979
    PubMed
    Summary
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    Bone mineral content in patients with hematological diseases did not significantly differ from normal groups. Peripheral measurement sites and late compacta involvement may explain these findings in bone destruction.

    Area of Science:

    • Hematology
    • Radiology
    • Bone Densitometry

    Context:

    • Hematological systemic diseases can cause significant bone changes, including osteoporoses, osteolytic processes, and vertebral deformities.
    • Radiological and histological methods are typically used to diagnose these bone alterations.
    • Assessing bone mineral content is crucial for understanding disease impact.

    Purpose:

    • To evaluate bone mineral content in patients with hematological diseases using J-125 absorption measurements.
    • To investigate the relationship between hematological diseases and bone destructions.
    • To identify potential reasons for discrepancies in bone density measurements.

    Summary:

    • Absorption measurements of monoenergetic rays from a J-125 source were conducted on 461 patients with various hematological diseases.

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  • Results indicated no significant difference in bone mineral content between patients with bone destructions and a normal group.
  • The study suggests that the measurement location (distal radius and ulna) and the late involvement of compact bone in the disease process may account for the observed results.

    • Impact:

    • Highlights the limitations of peripheral bone densitometry in detecting bone changes associated with hematological diseases.
    • Suggests that more central measurement sites might be necessary for accurate assessment.
    • Informs future research on optimal methods for evaluating bone health in hematological patients.