Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pubertal neurocranium growth in thymectomized rats.

W Rino, D Teixeira

    Acta Anatomica
    |January 1, 1979
    PubMed
    Summary

    Thymectomy, the removal of the thymus gland, significantly stunts neurocranium growth in rats. This effect on skull development was observed in both male and female rats across various ages.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The relationships between passions, intentions, habit and exercise frequency.

    Journal of sports sciences·2023
    Same author

    The relationship between past exercise behavior and future exercise adherence: A sequential mediation analysis.

    Journal of sports sciences·2022
    Same author

    Explosive nosocomial outbreak of SARS-CoV-2 in a rehabilitation clinic: the limits of genomics for outbreak reconstruction.

    The Journal of hospital infection·2021
    Same author

    Adaptation and Validation of a Portuguese Version of the Sports Motivation Scale-II (SMS-II-P) Showing Invariance for Gender and Sport Type.

    Perceptual and motor skills·2021
    Same author

    Evaluating the prevalence of tail biting and carcase condemnations in slaughter pigs in the Republic and Northern Ireland, and the potential of abattoir meat inspection as a welfare surveillance tool.

    The Veterinary record·2012
    Same author

    High prevalence of the GSTM3*A/B polymorphism in sub-Sarahan African populations.

    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2010

    Area of Science:

    • Developmental biology
    • Endocrinology
    • Comparative anatomy

    Background:

    • The thymus gland plays a crucial role in immune system development.
    • Its influence on skeletal growth, particularly cranial development, is not fully understood.
    • Pubertal growth is a critical period for skeletal maturation.

    Purpose of the Study:

    • To investigate the impact of thymectomy on neurocranium growth during puberty in rats.
    • To determine if thymectomy affects skull dimensions in a sex-dependent manner.
    • To compare cranial development in thymectomized, sham-thymectomized, and control rats.

    Main Methods:

    • Rats of both sexes underwent thymectomy or sham-thymectomy at various ages (2-14 days).
    • Skull measurements including length, width, height, skull base length, and face length were recorded.
    • Data were analyzed to compare cranial dimensions between experimental groups and controls.

    Main Results:

    • Thymectomized rats exhibited significantly smaller neurocranium dimensions compared to sham-thymectomized and control groups.
    • This reduction in skull size was consistent across both sexes and all studied age groups.
    • Specific measurements affected included skull length, width, height, skull base length, and face length.

    Conclusions:

    • Thymectomy during early life significantly impairs neurocranium development in rats.
    • The thymus gland appears to be a critical factor influencing pubertal skull growth.
    • These findings suggest a potential link between thymic function and skeletal maturation.

    Related Experiment Videos