Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone marrow necrosis.

M E Conrad, J T Carpenter

    American Journal of Hematology
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Bone marrow necrosis is a common finding, often overlooked, in patients with various disorders. This condition may lead to bone marrow fibrosis and idiopathic myelofibrosis, requiring further investigation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    What is expert nursing care? a nursing director's viewpoint.

    The American journal of nursing·2010
    Same author

    Krukenberg tumors.

    Delaware state medical journal·2010
    Same author

    Iron absorption: relative importance of iron transport pathways.

    American journal of hematology·2001
    Same author

    Separate pathways for cellular uptake of ferric and ferrous iron.

    American journal of physiology. Gastrointestinal and liver physiology·2000
    Same author

    Abnormalities of flavin monooxygenase as an etiology for sideroblastic anemia.

    American journal of hematology·2000
    Same author

    Iron absorption and transport-an update.

    American journal of hematology·2000
    Same journal

    Relapse Thresholds (12/24 Mo) Define Survival Disparity in Pediatric B-ALL.

    American journal of hematology·2026
    Same journal

    Quizartinib in Combination With FLAG-IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG-QUIDA): A PETHEMA Phase I-II Trial.

    American journal of hematology·2026
    Same journal

    Defining a Subgroup of Myelodysplastic Syndrome Patients With Very Poor-Risk Cytogenetics Demonstrating a Relatively More Favorable Outcome After Allogeneic Hematopoietic Cell Transplantation.

    American journal of hematology·2026
    Same journal

    Safety and Efficacy of Plerixafor in Poor Mobilizers With Lymphoma: A Multicenter, Prospective, Single-Arm Study.

    American journal of hematology·2026
    Same journal

    Dordaviprone Maintenance After Allogeneic HCT for High-Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm.

    American journal of hematology·2026
    Same journal

    Early Treatment Failure in Patients Receiving Ciltacabtagene-Autoleucel for Relapsed/Refractory Multiple Myeloma.

    American journal of hematology·2026
    See all related articles

    Area of Science:

    • Hematology
    • Pathology
    • Oncology

    Background:

    • Bone marrow necrosis (BMN) is traditionally considered rare in living patients, often linked to poor prognosis.
    • This study challenges that notion, proposing BMN is a frequent, overlooked finding in diverse acute and chronic conditions.

    Purpose of the Study:

    • To re-evaluate the incidence and clinical significance of bone marrow necrosis.
    • To explore the potential link between BMN, bone marrow fibrosis, and idiopathic myelofibrosis.

    Main Methods:

    • Review of bone marrow specimens from patients with various acute and chronic disorders.
    • Histopathological analysis to identify bone marrow necrosis and associated changes.

    Main Results:

    Related Experiment Videos

  • Bone marrow necrosis is identified as a common finding in bone marrow specimens.
  • The condition occurs across a spectrum of acute and chronic diseases and is frequently missed.
  • Prolonged BMN may predispose to bone marrow fibrosis and idiopathic myelofibrosis.

    • Conclusions:

    • Bone marrow necrosis is an under-recognized entity with potential implications for disease diagnosis and prognosis.
    • Further research is needed to elucidate the role of BMN in disease pathophysiology and its diagnostic utility.