Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

"Antidotal thirst": a response to intoxication.

D F Smith, S Balagura, M Lubran

    Science (New York, N.Y.)
    |January 16, 1970
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A Case of Hydatids of the Lungs.

    The Independent practitioner·2023
    Same author

    Facing up to a problem with recognition.

    British journal of hospital medicine (London, England : 2005)·2019
    Same author

    Quantitative analysis of the functional relationships existing between ecosystem components : I. Analysis of the Linear Intercomponent Mass Transfers.

    Oecologia·2017
    Same author

    (14)C-labeling of the compounds excreted by phytoplankton for employment as a realistic tracer in secondary productivity measurements.

    Microbial ecology·2013
    Same author

    Comments on "peroxyisobutyryl nitrate".

    Environmental science & technology·2011
    Same author

    Meta-analysis on anxiety and depression in adult celiac disease.

    Acta psychiatrica Scandinavica·2011
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    Albino rats drank more water after ingesting lithium chloride. This thirst response aids in the body

    Area of Science:

    • Physiology
    • Toxicology
    • Renal Science

    Background:

    • Lithium chloride is a compound that can induce physiological changes.
    • Understanding the body's response to toxic substances is crucial for toxicology and medicine.

    Purpose of the Study:

    • To investigate the immediate effects of lithium chloride ingestion on water intake in albino rats.
    • To explore the physiological mechanisms underlying thirst induced by lithium chloride.

    Main Methods:

    • Administration of a 0.12 molar lithium chloride solution to albino rats.
    • Monitoring of water intake following lithium chloride administration.
    • Analysis of blood volume and tonicity to rule out their contribution to thirst.

    Main Results:

    Related Experiment Videos

    • A significant increase in water intake was observed shortly after oral administration of lithium chloride.
    • Changes in blood volume and tonicity did not fully explain the observed level of thirst.
    • The heightened thirst facilitated the excretion of lithium ions via the kidneys.

    Conclusions:

    • Increased water intake following lithium chloride ingestion is a physiological response to facilitate toxic ion excretion.
    • This thirst mechanism plays a role in mitigating lithium toxicity.