[A modified method for the determination of locations of chronically implanted electrodes in rabbit brains (author's...

A fast and simple method is described for the localisation of tips of chronically implanted electrodes in the brain of rabbits which may be obtained--under standard conditions--by an intra-aortal injection of a 2% potassium-hexacyanoferrate-III solution. This method also facilitates histological preparations with a thickness of 5 mu only and thus permits a thorough morpho-pathological examination not only in the area of the electrode tips but in adjacent zones as well. The use of a buffered formalin solution also permits certain histochemical examinations to be made, for instance the determination of nucleic acids.