Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The gallium "bone scan" in acute leukemia.

G F Gates

    Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
    |August 1, 1979
    PubMed
    Summary

    Gallium-67 scans in a boy with acute leukemia showed extensive bone uptake, mimicking bone scans. This pattern suggests leukemia cells infiltrating the bone marrow, a key diagnostic indicator.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Bone SPECT of the back after lumbar surgery.

    Clinical nuclear medicine·1999
    Same author

    Consensus report on quality control of quantitative measurements of renal function obtained from the renogram: International Consensus Committee from the Scientific Committee of Radionuclides in Nephrourology.

    Seminars in nuclear medicine·1999
    Same author

    SPECT bone scanning of the spine.

    Seminars in nuclear medicine·1998
    Same author

    Bone SPECT imaging of the painful back.

    Clinical nuclear medicine·1996
    Same author

    Oblique angle bone SPECT imaging of the lumbar spine, pelvis, and hips. An anatomic study.

    Clinical nuclear medicine·1996
    Same author

    Radionuclide renal imaging in the United States.

    European journal of nuclear medicine·1995

    Area of Science:

    • Nuclear Medicine
    • Oncology
    • Radiology

    Background:

    • Acute leukemia can infiltrate bone marrow.
    • Gallium-67 citrate and technetium-99m pyrophosphate are radiopharmaceuticals used in bone imaging.

    Observation:

    • A 15-year-old male patient with acute leukemia underwent gallium-67 scintigraphy.
    • The gallium-67 scan demonstrated extensive osseous uptake, similar to a concurrent technetium-99m pyrophosphate bone scan.
    • Renal visualization was notably absent on the gallium-67 scan.

    Findings:

    • The observed extensive bone uptake on gallium-67 scintigraphy is attributed to leukemic cell infiltration of the bone marrow.
    • The similarity between gallium-67 and technetium-99m pyrophosphate scans in this case highlights a specific imaging pattern.
    • Radiopharmaceutical quality was confirmed through a control scan.

    Implications:

    • This imaging pattern serves as a recognizable indicator of diffuse marrow-infiltrating disease in leukemia.
    • Nuclear medicine plays a crucial role in diagnosing and staging hematologic malignancies.
    • Recognition of this gallium-67 uptake pattern can aid in early detection and management of bone marrow infiltration.

    Related Experiment Videos