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Subcellular Fractionation for the Isolation of Synaptic Components from the Murine Brain
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Protein synthesis in fractions from isolated brain cell nuclei

J A Burdman, K Haglid, A R Dravid

    Journal of Neurochemistry
    |May 1, 1970
    PubMed
    Abstract

    No abstract available in PubMed .

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    The homogenate obtained after cell lysis contains various membrane-bound organelles that can be further separated into pure fractions by subcellular fractionation. These isolates are used to study specific cellular components, analyze localized protein activity, and are even employed in diagnostics. Fractionation is typically achieved using centrifugation methods, the most common being density-gradient and differential centrifugation.
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