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Related Experiment Videos

Method for measuring cerebral dysfunction in patients with liver disease.

R Zeegen, J E Drinkwater, A M Dawson

    British Medical Journal
    |June 13, 1970
    PubMed
    Summary

    Cerebral function tests after portal decompression for intrahepatic portal hypertension revealed mild encephalopathy in 47% of patients. A modified Reitan trail making test proved more effective than star construction for assessing cognitive function.

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    Area of Science:

    • Neurology
    • Gastroenterology
    • Psychology

    Background:

    • Intrahepatic portal hypertension can lead to complications affecting cerebral function.
    • Portal decompression is a surgical intervention aimed at managing portal hypertension.
    • Assessing cognitive deficits post-surgery is crucial for patient management.

    Purpose of the Study:

    • To evaluate objective tests of cerebral function in outpatients following portal decompression.
    • To determine the prevalence of overt encephalopathy after the procedure.
    • To compare the efficacy of different cognitive tests.

    Main Methods:

    • Sixty-four outpatients undergoing portal decompression for intrahepatic portal hypertension were assessed.
    • Cognitive function was evaluated using a star construction test and a modified Reitan trail making test.

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  • Performance was scored based on errors made in each test.

    • Main Results:

    • The modified Reitan trail making test demonstrated greater discriminatory power than the star construction test.
    • Overt encephalopathy, generally mild, was observed in 30 patients (47%).
    • A correlation was found between test results and the presence of encephalopathy.

    Conclusions:

    • Objective cognitive testing is valuable in evaluating patients after portal decompression.
    • The modified Reitan trail making test is a useful tool for detecting subtle cerebral dysfunction.
    • Encephalopathy is a common, albeit often mild, complication following this surgical intervention.