[The slope clearance method in renal functional diagnosis. J-131-hippurate clearance is used as an example]

The clinical relevance of the clearance of radiopharmaca is controversial in literature. The cause for this are in our opinion the different methods of evaluation which either make difficult or make impossible a comparison of individual results. The late phase of the disappearance (at least 70 and 100 min p.i.) possesses a high value under the aspect of renal diagnosis, since by its means with a high approximation the renal function may be established itself.