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Symmetrical lipodystrophy with hypothyroidism.

J R Taylor, D Wilansky

    Annals of Plastic Surgery
    |June 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Benign symmetrical lipomatosis, a rare condition, is linked to hypothyroidism. Full thyroid investigation is recommended for patients, and renaming the disorder to symmetrical lipodystrophy may improve classification.

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    Area of Science:

    • Endocrinology
    • Dermatology
    • Metabolic Disorders

    Background:

    • Benign symmetrical lipomatosis (BSL) is a rare condition characterized by the symmetrical deposition of adipose tissue, primarily in the neck, shoulders, and upper trunk.
    • The etiology of BSL remains unclear, with potential links to genetic factors and metabolic disturbances.

    Observation:

    • This report details the case of a female patient diagnosed with benign symmetrical lipomatosis and co-existing hypothyroidism.
    • The patient's clinical presentation and treatment course were meticulously documented.

    Findings:

    • The case highlights a potential association between benign symmetrical lipomatosis and hypothyroidism, suggesting a shared underlying pathophysiology.
    • Thyroid dysfunction should be considered in the differential diagnosis of patients presenting with BSL.

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    Implications:

    • The findings suggest that comprehensive thyroid function tests are warranted in all patients diagnosed with benign symmetrical lipomatosis.
    • Renaming the condition to 'symmetrical lipodystrophy' is proposed to better reflect its nature as a fat deposition disorder and to distinguish it from lipomas, especially since no malignant variants have been reported.