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Updated: Aug 5, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Study of childhood urinary tract infection in general practice
Insights
This study found that urinary tract infections (UTIs) in children under 13 are common, especially before age 5. Many UTIs are asymptomatic, and some are linked to urinary tract abnormalities.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- General Practice
Background:
- Urinary tract infections (UTIs) are a significant health concern in children.
- Early detection and management are crucial to prevent long-term complications.
- The prevalence and characteristics of UTIs in pediatric populations require ongoing investigation.
Purpose of the Study:
- To determine the incidence and prevalence of bacteriuria in children under 13.
- To identify risk factors and clinical presentations associated with childhood UTIs.
- To assess the utility of pyuria and proteinuria in predicting asymptomatic bacteriuria.
Main Methods:
- A prospective study involving 426 children under 13 years old in a general practice.
- Screening for bacteriuria in the study population.
- Radiological investigation of children with confirmed UTIs.
- Analysis of clinical data, including symptoms and laboratory findings.
Main Results:
- The incidence of UTIs was 1.4% per annum, with a higher incidence of 4.9% per annum in children under 5.
- Asymptomatic bacteriuria was detected in three girls and one boy.
- Five other children had a history of UTIs; radiological abnormalities were found in 50% of investigated cases.
- Pyuria and proteinuria were not reliable predictors of asymptomatic bacteriuria.
Conclusions:
- Childhood UTIs are more prevalent than previously estimated, particularly in younger children.
- A significant proportion of UTIs in children may be asymptomatic and associated with renal tract abnormalities.
- Urinary tract infections with renal tract abnormalities are considerably more common than childhood diabetes.
Abstract:
A study of bacteriuria was conducted among 426 of the 436 children under the age of 13 in a general practice in north-west London. Three girls and one boy were found to have asymptomatic bacteriuria, and a further girl with bacteriuria presented with abdominal pain and fever. The calculated incidence of urinary tract infection was 1.4% per annum. Most of the childhood urinary infections in this practice occurred before the age of 5 years, and the incidence of significant bacteriuria in this age group was 4.9% per annum. Five other children (four girls and one boy) in the practice were known to have had proved urinary tract infection. Of the total of eight children known to have had significant bacteriuria and investigated radiologically, three girls and two boys had radiological abnormalities in the urinary tract.Pyuria and proteinuria did not prove to be useful in the prediction of asymptomatic bacteriuria. Urinary tract infection with renal tract abnormality was found in this practice to be at least five times as common as diabetes in childhood.
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