Related Experiment Video

Updated: Aug 14, 2026

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.
08:27

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.

Published on: January 27, 2015

Natural history and pathophysiology of arteriovenous malformations

W J Michelsen

    Clinical Neurosurgery
    |January 1, 1979
    PubMed

    AVMs are congenital malformations of central nervous system blood vessels. The majority of lesions become symptomatic prior to age 40. Hemorrhage and epilepsy are the most frequent presenting symptoms. Disabling headache, transient, progressive, and permanent neurological deficit, heart failure, hydrocephalus, macrocephaly, and intellectual impairment may also occur. Long-term mortality is approximately 18%, and morbidity leading to disability occurs in 30% of patients. Aggressive management when possible is indicated.

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