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Related Experiment Videos

Multiple bleeds in haemophilia A.

A Aronstam, M J Painter, J V Eddey

    Clinical and Laboratory Haematology
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Simultaneous bleeding in two sites occurred in 3.7% of episodes. Elbows, knees, and ankles were most common, with less transfusion need than single bleeds.

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    Area of Science:

    • Hematology
    • Orthopedic Surgery
    • Clinical Medicine

    Background:

    • Joint and soft tissue bleeding are common complications.
    • Understanding patterns of multiple bleeding sites is crucial for patient management.

    Purpose of the Study:

    • To analyze the incidence and characteristics of simultaneous double bleeds.
    • To identify common sites and factors influencing transfusion needs in double bleeds.

    Main Methods:

    • Retrospective analysis of 4935 bleeding episodes.
    • Documented incidence of simultaneous two-site bleeding.
    • Identified common anatomical locations for double bleeds.
    • Assessed transfusion requirements for single versus double bleeds.

    Main Results:

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    • 181 episodes (3.7%) involved simultaneous bleeding at two sites.
    • Elbows, knees, and ankles were most frequently involved in double bleeds.
    • Thigh, upper arm, and elbow were most common in double bleeds requiring transfusions.
    • Overall transfusion requirements were lower for double bleeds compared to single bleeds.
    • Multiple bleed frequency correlated with overall bleeding frequency, not observation duration.

    Conclusions:

    • Simultaneous double bleeds represent a significant subset of bleeding episodes.
    • Specific joints are predisposed to double bleeds.
    • Double bleeds may require fewer transfusions than single bleeds, suggesting potential differences in severity or management.
    • Bleeding frequency is a key predictor of multiple bleeding site occurrence.