Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Cardiac Cycle01:13

The Cardiac Cycle

77.5K
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
77.5K
Chambers of the Heart01:16

Chambers of the Heart

10.0K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
10.0K
Heart Valves01:16

Heart Valves

14.9K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
14.9K
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

1.3K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.3K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.9K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

753
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
753

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of lactogenic activity in the serum of the squirrel monkey (Saimiri boliviensis) using the Nb2 lymphoma bioassay.

American journal of primatology·2020
Same author

Characterization of prolactin and growth hormone immuno- and bioactivities in the pituitary gland and serum of the squirrel monkey (Saimiri boliviensis boliviensis).

American journal of primatology·2020
Same author

Risk factors for bronchiolitis: Presentation of an on-going prospective clinical study.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2016
Same author

Variance decomposition: a tool enabling strategic improvement of the precision of analytical recovery and concentration estimates associated with microorganism enumeration methods.

Water research·2014
Same author

On the estimation of phosphorus from the Niagara River to Lake Ontario.

Environmental monitoring and assessment·2013
Same author

Molecular assessment of heterotrophy and prey digestion in zooxanthellate cnidarians.

Molecular ecology·2013

Related Experiment Video

Updated: May 4, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

2.8K

Left atrial booster function in valvular heart disease.

F P Heidenreich, J A Shaver, M E Thompson

    The Journal of Clinical Investigation
    |September 1, 1970
    PubMed
    Summary
    This summary is machine-generated.

    Atrial booster pump action significantly benefits patients with valvular heart disease. Impairing this function, even with intact reservoir function, reduces hemodynamic measurements, confirming its crucial role.

    More Related Videos

    Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
    08:49

    Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

    Published on: August 2, 2024

    1.4K
    Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
    07:28

    Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

    Published on: October 11, 2024

    876

    Related Experiment Videos

    Last Updated: May 4, 2026

    Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
    08:10

    Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

    Published on: July 20, 2022

    2.8K
    Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
    08:49

    Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

    Published on: August 2, 2024

    1.4K
    Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
    07:28

    Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

    Published on: October 11, 2024

    876

    Area of Science:

    • Cardiology
    • Cardiac Physiology

    Background:

    • Valvular heart disease impacts cardiac function.
    • Atrial function includes reservoir-conduit and booster pump roles.

    Purpose of the Study:

    • To assess the impact of atrial booster pump action in valvular heart disease.
    • To differentiate booster pump function from reservoir-conduit function.

    Main Methods:

    • Sequential atrioventricular (A-V) pacing in patients with aortic or mitral stenosis.
    • Hemodynamic measurements including valvular gradient, flow, and ventricular work/pressure.
    • Interventions included eliminating atrial contraction and synchronous A-V pacing.

    Main Results:

    • Eliminating atrial contraction significantly reduced valvular gradient, flow, and ventricular function.
    • Synchronous A-V pacing (eliminating effective atrial systole) also significantly reduced hemodynamic measurements.
    • Impairing booster pump action alone caused significant hemodynamic reduction, comparable to impairing both functions.

    Conclusions:

    • Atrial booster pump action provides significant hemodynamic benefits in valvular heart disease.
    • Well-timed atrial contraction plays a crucial role in maintaining cardiac output.
    • Understanding atrial function is key for managing valvular heart disease.