[Generalization of leg eczema]

Extensive secondary eczema of the legs and chronic venous insufficiency coexist fairly often ; among aetiological factors are considered atopy and multiple sensitivities, contact dermatitis, and eczematizations of infective origin (bacterial or fungal) from organisms with weak pathogenic potency but strong allergenic potency. There is a short clinical description referring to the phenomena of primary irritation and controlateral extensions of the eczema. The pathogenesis relates to immunological phenomena and antigen-antibody conflicts. These types of eczema come for the most part into the category of delayed hypersensitivity type IV of the Gell-Coombs classification.