Insulin-stimulated glucose uptake by subcellular particles from adipose tissue cells

Microsomal particles prepared from isolated rat adipose cells take up D-glucose more rapidly than L-glucose. The rate of D-glucose uptake, but not that of L-glucose, is stimulated by incubation of the intact cells with insulin at concentrations as low as 10 microunits per milliliter before disruption and preparation of the microsomes.