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Related Experiment Videos

Transient traumatic "locked-in" syndrome.

B Chang, M A Morariu

    European Neurology
    |January 1, 1979
    PubMed
    Summary

    Transient traumatic locked-in syndrome, a rare condition, can last months. This case suggests brain stem injuries from trauma may offer a better prognosis than those from artery blockages.

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    Area of Science:

    • Neuroscience
    • Clinical Neurology
    • Trauma Medicine

    Background:

    • Locked-in syndrome (LIS) is a severe neurological condition characterized by immobility and inability to communicate.
    • Traditionally, LIS is associated with poor prognosis, often linked to vascular events like basilar artery occlusion.

    Purpose of the Study:

    • To present the first clinical case of transient traumatic locked-in syndrome.
    • To investigate the clinical presentation, neurophysiological findings, and prognosis of traumatic LIS.

    Main Methods:

    • Case report of a patient with transient LIS.
    • Clinical neurological examination.
    • Auditory evoked response testing to localize the brain lesion.

    Main Results:

    • The patient experienced a 3-month locked-in state following trauma.
    • Neurological deficits and abnormal auditory evoked responses indicated a lesion in the left pons and ventral midbrain.
    • Recovery from the transient LIS was implied by the case presentation.

    Conclusions:

    • Traumatic brain stem damage can result in a transient locked-in syndrome.
    • Transient traumatic LIS may have a more favorable prognosis compared to LIS caused by basilar artery occlusion.

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