[Electrocardiographic manifestations of ventricular diastolic depolarization. Clinico-experimental study]

Several haemodynamic and biochemical parameters were studied in order to explain the diagnostic value of the electrocardiographic abnormalities in partial myocardial diastolic depolarization, in different conditions, as experimental coronary oclussion, adrenalinic effects, tachycardia, hypoxia and shock. It is concluded that the electrocardiographic signs of diastolic depolarization (injury tissue) are: RS-T deplacement, conduction disturbances at bundle, fascicular and muscular levels, as well as ventricular ectopic beats. The experimental findings were correlated with clinical cases showing electrocardiographic signs of ventricular diastolic depolarization, as in myocardial infarct, angina pectoris, hypertensive heart disease, pheocromocitoma and tachycardia. It is concluded that the oxygen volume available at mitochondrial level is diminished, if it is correlated to the metabolic and/or haemodynamic alterations.